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28. “Organocatalytic Asymmetric Annulation of ortho-Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-Indoles”  L. Peng, K. Li, C. Xie, S. Li, D. Xu, W. Qin, Hailong Yan* Angew. Chem. Int. Ed. 2019, 10.1002/anie.201908961. PDF


27. “Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond To Form Two Stereogenic Centers in an Aqueou Medium” Z. Chen, F. Hu, S. Huang, Z. Zhao, H. Mao* and W. Qin* J. Org. Chem. 2019, 84, 81008111 . PDF


26. “Metal-free difunctionalization of alkynes to access tetrasubstituted olefins through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM)” S. Huang, Z. Chen, H. Mao, F. Hu, D. Li, Y. Tan, F. Yang, W. Qin* Org. Biomol. Chem. 2019, 10.1039/c8ob02967a. PDF


25. “Organocatalytic Atropo- and E/Z-selective Michael Addition Reaction of Ynones with α-Amido Sulfones as Sulfone-type Nucleophile” N. Zhang, T. He, Y. Liu, S. Li, Y. Tan, L. Peng, D. Li,  C. Shan, Hailong Yan* Org. Chem. Front. 2018, 10.1039/c8qo01241e. PDF


24. “Asymmetric One-Pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes, and Chirality of Axial Styrenes” A. Huang, Li. Zhang, D. Li, Y. Liu*, Hailong Yan* and W. Li* Org. Lett. 2018, 10.1021/acs.orglett.8b03492. PDF


23. “Kinetic Resolution of Allylic Alcohol with Chiral BINOL-based Alkoxides: A Combination of Experimental and Theoretical Studies” Y. Liu, S. Liu, D. Li, N. Zhang, L. Peng, J. Ao,  C. E. Song, Y. Lan and Hailong Yan* J. Am. Chem. Soc. 2018, 10.1021/jacs.8b12796. PDF


22. “Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis” Y. Tan, S. Jia, F. Hu, Y. Liu, L. Peng, D. Li and Hailong Yan* J. Am. Chem. Soc. 2018,10.1021/jacs.8b09893. PDF


21. “Organocatalytic Asymmetric Atroposelective Construction of Axially Chiral 1,4-Distyrene 2,3-Naphthalene Diols” S. Li, D. Xu, F. Hu, D. Li, W. Qin, Hailong Yan* Org. Lett. 2018, 10.1021/acs.orglett.8b03398. PDF


20. “Organocatalytic Asymmetric One-Step Desymmetrizing Dearomatization Reaction of Indoles: Development and Bioactivity Evaluation”  L. Peng, D. Xu, X. Yang, J. Tang, X. Feng*, S. Zhang*, Hailong Yan* Angew. Chem. Int. Ed. 2018, 10.1002/anie.201811437. PDF


19. “Asymmetric Mannich Reaction and Construction of Axially Chiral Sulfone-Containing Styrenes in One Pot from αAmido Sulfones Based on the WasteReuse StrategyD. Li, Y. Tan, L. Peng, S. Li, N. Zhang, Y. Liu, Hailong Yan* Org. Lett. 201820, 4959-4963. PDF


18. “Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes” N. Zhang, Y. Li, Z. Chen, W. Qin Synthesis 2018, just accepted.


17. “Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes” S. Jia, Z. Chen, N. Zhang, Y. Tan, Y. Liu, J. Deng, H. Yan* J. Am. Chem. Soc. 2018, DOI: 10.1021/jacs.8b03211.


16. “Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls” Y. Liu, X. Wu, S. Li, L. Xue, C. Shan, Z. Zhao, H. Yan* Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201801824.


15. “Enantioselective Addition of Selenosulfonates to α,β-unsaturated Ketones” S. Luo, N. Zhang, Z. Wang, H. Yan* Org. Biomol. Chem. 2018, just accepted罗世龙OBC

14. “Enantioselective one-pot synthesis of β-sulfonyl ketones and trisubstituted tetrahydrothiophenes via β-elimination/cycloaddition sequence” L. Xue, Y. Liu, W. Qin, H. Yan* Chinese Chemical Letters 2018doi.org/10.1016/j.cclet.2018.01.047


13. “Acid-promoted furan annulation and aromatization: an access to benzo[b]furan derivatives” J. Ao, Y. Liu, S. Jia, L. Xue, D. Li, Y. Tan, W. Qin*, H. Yan* Tetrahedron 2018, 74, 433-440. PDF


12. “Organocatalytic Intramolecular [4+2] Cycloaddition Between In-situ Generated Vinylidene ortho-Quinone Methide and Benzofuran” X. Wu, L. Xue, D. Li, S. Jia, J. Ao, J. Deng, H. Yan* Angew. Chem. Int. Ed. 2017, 5613722 –13726. PDF


11.  “Asymmetric Aminalization via Cation-Binding Catalysis ”  S. Y. Park, Y. Liu, J. S. Oh, Y. K. Kweon,. Y. B. Jeong, M. Duan, Y. Tan,. J.-W. Lee,* H. Yan,* C. E. Song* Chem. Eur. J. 2017, just accepted. Cover Paper PDF
Asymmetric Aminalization via Cation‐Binding Catalysis


10. “K2S2O8 Activated Friedel-Crafts Type Alkylation of Indoles with α-Amido Sulfones” X. Wu, L. Xue, S. Luo, S. Jia, J. Ao, W. Qin* Synthesis, 2017, 49, 5017-5024. PDF



9. “Fluoride Anions in Self-Assembled Chiral Cage for the Enantioselective Protonation of Silyl Enol Ethers”  S. Paladhi, Y. Liu, B. S. Kumar, M.-J. Jung, S. Y. Park, H. Yan* and C. E. SongOrg. Lett. 2017, 19, 3279-3282.  PDF


8. “Enantioselective Synthesis of antisyn-Trihalides and antisynanti-Tetrahalides via Asymmetric β-Elimination,” Y. Tan, S. Luo, D. Li, N. Zhang, S. Jia, Y. Liu, W. Qin, C. E. Song and H. Yan* J. Am. Chem. Soc. 2017, 139, 6431.  PDF


7.  “Asymmetric Synthesis of Trisubstituted Tetrahydrothiophenes via in-situ Generated Chiral Fluoride Catalyzed Cascade Sulfa-Michael/Aldol Reaction of 1,4-dithiane-2,5-diol and α,β-Unsaturated Ketones,” M. Duan, Y. Liu, J. Ao, L. Xue, S. Luo, Y. Tan, W. Qin, C. E. Song and H. Yan* Org. Lett. 2017, 19, 2298.  PDF


6.  “Asymmetric Synthesis of α-Thiocyanato-β-keto-amines with Tetrasubstituted Carbon Stereogenic Centers via Cooperative Cation-Binding Catalysis, ” L. Yu, X. Wu, M. J. Kim, V. Vaithiyanathan, Y. Liu, Y. Tan, W. Qin, C. E. Song* and H. Yan*  Adv. Synth. Catal. 2017, 359, 1879-1891. PDF

5. “Cooperative Cation-Binding Catalysis as an Efficient Approach for Enantioselective Friedel-Crafts Reaction of Indoles and Pyrrole,” M. J. Kim; L. Xue; Y. Liu; S. Paladhi; S. J. Park; H. Yan* and C. E. Song*  Adv. Synth. Catal.  2017, 359, 811-823.  PDF


4. “Direct Access to Chiral β-Fluoroamines with Quaternary Stereogenic Center through Cooperative Cation-Binding Catalysis,”  V. Vaithiyanathan; M. J. Kim; Y. Liu; H. Yan* and C. E. Song* Chem. Eur. J. 2017, 23, 1268-1272.  PDF


3. “Organocatalytic Asymmetric Synthesis of Chiral Dioxazinanes and Dioxazepanes with In Situ generated Nitrones via Tandem Reaction Pathway using a Cooperative Cation Binding Catalyst,”  Y. Liu; J. Ao; S. Paladhi; C. E. Song* and Hailong Yan*  J. Am. Chem. Soc. 2016, 138, 16486-16492.  PDF


2.  “Efficient Enrichment of Chiral β-Sulfonyl Ketones through Asymmetric β-Elimination,”  Y. Liu; W. Qin and H. Yan* Synlett 201627, 2756-2760.  PDF


1.  “Kinetic Resolution of β-Sulfonyl Ketones through Enantioselective β-Elimination using a Cation-Binding Polyether Catalyst,” L. Li; Y. Liu; Y. Peng; L. Yu; X. Wu and H. Yan* Angew. Chem. Int. Ed. 2016, 55, 331–335.  PDF